Slow Cooker Cajun Chicken Fettuccine

Slow Cooker Cajun Chicken Fettuccine is a great spicy recipe for pasta night!

This slow cooker Cajun chicken fettuccine was one of the those recipes that changed after the ingredients were bought. I had planned to make a dish called chicken lazone, but decided to add a few more Cajun seasonings then add pasta and Parmesan cheese to the pot at the end of the cooking time along with the cream

Prep time 25 mins

Cook time 6 hours 20 mins

Total time 6 hours 45 mins  

Serves: 6


  • 1 cup chicken broth
  • ¼ tsp. cayenne pepper
  • ½ tsp. garlic powder
  • ¼ tsp. onion powder
  • ½ tsp. dried leaf oregano
  • ¼ tsp. red pepper flakes
  • 1½ tsp. paprika
  • 1 tsp. salt
  • ¼ tsp. pepper
  • 1.5 – 2 lbs. boneless skinless chicken breasts
  • 1 small white onion, diced

Add at the end

  • 1 lb. fettuccine noodles, cooked according to package directions
  • 2 cups heavy cream
  • ¾ cup parmesan cheese, divided

Slow Cooker Size:

  • 6-quart or larger


  1. Add the chicken broth to the slow cooker, add the cayenne, garlic powder, onion powder, oregano, red pepper flakes, paprika, salt and pepper. Stir.
  2. Add the chicken breasts and flip them around in the seasoned chicken broth to get the seasonings on the chicken.
  3. Sprinkle the onions over the chicken and broth.
  4. Cover and cook on low for 6 hours without opening the lid during the cooking time.
  5. After the cooking time is done, add the heavy cream and shred the chicken with 2 forks right in the slow cooker.
  6. Add the cooked and drained pasta and a ½ cup of the Parmesan cheese. Stir.
  7. Sprinkle over the remaining parmesan cheese. I added a touch more paprika and also parsley flakes to the top of my pasta to make it look pretty. Cover and cook for 20 more minutes. Cooking for a bit longer helps the sauce thicken from the gluten in the pasta.
  8. Serve and enjoy!